The book can be found on the desk in the Mayor’s office on the top floor of the building. Later, diverting HELIOS One’s power to the entire region will reward you with the Skill Book. Players can find this book on a desk in the command center. There is a hidden cellar in the back of this shack, where this book can be found on a table with the chemistry set.
The Big Book of Science permanently increases a player’s Science Skill. This guide will show you how to find each of the Fallout New Vegas skill books.
There are three to five copies of each in the base game, but with all DLCs installed, that number goes up by a varying number.
There are a total of thirteen different types of Skill Books in New Vegas, and each of these then have a set number of copies that exist within the game.